Yes they are. Some scientists have recently demonstrated this phenomenon using a small study. It is now possible for the sum of about four dollars to determine from a single urine sample or blood if the person has an addiction or not. The test can at least be used in clinics because it gives the information of the normal levels of drug metabolites in the tissue of the consumer who uses improper doses, the casual consumer and the person who is trying to stop his drug use.
Once we had an inexpensive technology that allows us to measure levels of metabolites, we were able to calculate the curves'' disposal''.
Take the time of normal elimination of cocaine in a cocaine addict. Rates of metabolites in body fluids stay 15 to 16 days before dropping to zero. As for the methamphetamine the sample can have 3000 ng of amphetamine metabolites in his urine on day 1. After 25 days all metabolites are eliminated. Another example is phencyclidine metabolites. The sample may have initially 500 ng of metabolites. After 43 days there will still be traces.
There are the real scientific data allowing us to conclude that these substances are stored in the body and the detoxification'' or'' weaning should be taken.
How can the body eliminate these metabolites?
On day 1 the cocaine begins to detox.
On day 5 or 6, it manages to eliminate all metabolites.
Guess what happens then?
On day 6 or 7 the site receptors are no longer covered with dopamine or metabolites of cocaine. So the addict suffers from withdrawal effects and feels a craving. He makes another attempt to detox in 19 days. He repeats this cycle four or five times at intervals of about six or eight weeks before he will be able successfully kick the habit completely.
In summary, soluble metabolites are stored in tanks. And it is important to know that these tanks are not limited only to adipose tissue. Indeed, these metabolites are also stored in brain tissue, adrenal glands, nerve endings, in short, throughout the body. And these metabolites become poor substitutes for natural chemicals.